Trk A (Phospho-Y496) Rabbit pAb
  • Trk A (Phospho-Y496) Rabbit pAb
ELK

Trk A (Phospho-Y496) Rabbit pAb

Ref: ELK-ES12561-100μL
100μL

Información del producto

Trk A (Phospho-Y496) Rabbit pAb

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Información adicional
Storage Conditions -20°C/1 year
Applications ELISA
IF
WB
Concentration 1 mg/ml
Recomended Dilution ELISA 1:5000-20000
IF/ICC 1:100-500
WB 1:500-2000
Type Clonality Polyclonal
Immunogen Synthesized pospho peptide derived from human Trk A (Phospho-Y496)
Subcellular Location Cell membrane
Single-pass type I membrane protein . Early endosome membrane
Single-pass type I membrane protein . Late endosome membrane
Single-pass type I membrane protein . Rapidly internalized after NGF binding (PubMed:1281417). Internalized to endosomes upon binding of NGF or NTF3 and further transported to the cell body via a retrograde axonal transport. Localized at cell membrane and
Single-pass type I membrane protein . Recycling endosome membrane
Iso type IgG
Tissue Source Rabbit
Reactivity Human
Mouse
Rat
Human Gen 4914
Observed Band 180kD
Other Name High affinity nerve growth factor receptor (EC 2.7.10.1
Neurotrophic tyrosine kinase receptor type 1
TRK1-transforming tyrosine kinase protein
Trk-A
Tropomyosin-related kinase A
Tyrosine kinase receptor
Tyrosine kinase receptor A
gp140trk
p140-TrkA)
Background This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to ce