Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IF
IP
WB
IP
WB
Concentration
1 mg/ml
Recomended Dilution
IF/ICC 1:100-500
IP 1:50-200
WB 1:500-2000
IP 1:50-200
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human TRPV2 AA range: 493-543
Subcellular Location
Cell membrane
Multi-pass membrane protein . Cytoplasm . Melanosome . Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
Multi-pass membrane protein . Cytoplasm . Melanosome . Translocates from the cytoplasm to the plasma membrane upon ligand stimulation (By similarity). Identified by mass spectrometry in melanosome fractions from stage I to stage IV. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
51393
Observed Band
85kD
Other Name
Transient receptor potential cation channel subfamily V member 2 (TrpV2) (Osm-9-like TRP channel 2) (OTRPC2) (Vanilloid receptor-like protein 1) (VRL-1)
Background
This gene encodes an ion channel that is activated by high temperatures above 52 degrees Celsius. The protein may be involved in transduction of high-temperature heat responses in sensory ganglia. It is thought that in other tissues the channel may be act