Storage Conditions
-20°C/1 year
Applications
ELISA
WB IF
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 IF 1:100-300 ELISA 1:5000-20000 Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein. AA350-400
Subcellular Location
Cell membrane
Multi-pass membrane protein . Cell junction, tight junction .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
100506658
Observed Band
57kD
Background
This gene encodes an integral membrane protein that is required for cytokine-induced regulation of the tight junction paracellular permeability barrier. Mutations in this gene are thought to be a cause of band-like calcification with simplified gyration a