Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ELISA 1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Subcellular Location
Single-pass type I membrane protein .
Single-pass type I membrane protein .
Single-pass type I membrane protein .
Single-pass type I membrane protein . Requires the partner CD8A for efficient cell surface expression (PubMed:3145196). The heterodimer CD8A/CD8B localizes to lipid rafts due to CD8B cytoplasmic tail palmitoylation. .
[Isoform 1]: Cell membrane
[Isoform 2]: Cell membrane
[Isoform 3]: Secreted .
[Isoform 4]: Cell membrane
[Isoform 5]: Cell membrane
[Isoform 6]: Secreted .
[Isoform 7]: Secreted .
[Isoform 8]: Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
926
Observed Band
23kD
Background
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize an