Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ELISA 1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 21-70
Subcellular Location
Cytoplasm . Nucleus . Mainly cytoplasmic (PubMed:16876127, PubMed:16990255). Accumulates in the nucleus in response to influenza A virus (IAV) infection: senses IAV defective viral genomes RNA in the nucleus (By similarity). .
[Isoform 7]: Cytoplasm . Nucleus . Compared to isoform 1, a higher proportion of this isoform is localized in the nucleus. .
[Isoform 7]: Cytoplasm . Nucleus . Compared to isoform 1, a higher proportion of this isoform is localized in the nucleus. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
81030
Observed Band
47kD
Background
This gene encodes a Z-DNA binding protein. The encoded protein plays a role in the innate immune response by binding to foreign DNA and inducing type-I interferon production. Alternatively spliced transcript variants encoding multiple isoforms have been o