Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ELISA 1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 130-210
Subcellular Location
Single-pass type I membrane protein.
[Heparin-binding EGF-like growth factor]: Secreted, extracellular space. Mature HB-EGF is released into the extracellular space and probably binds to a receptor.
[Proheparin-binding EGF-like growth factor]: Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1839
Observed Band
22kD
Background
function:May be involved in macrophage-mediated cellular proliferation. It is mitogenic for fibroblasts and smooth muscle but not endothelial cells. It is able to bind EGF receptors with higher affinity than EGF itself and is a far more potent mitogen for