Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ELISA 1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Subcellular Location
Cytoplasmic vesicle membrane
Multi-pass membrane protein . Cytoplasm, cytoskeleton. Nucleus. Catalytically active full-length phosphorylated isoform 1 localizes to microtubules in the cytoplasm predominantly on microtubule cables positioned around the nucleus. A C-terminally truncate
[Isoform 2]: Cell projection, dendrite. In dendrites, colocalizes with PCDH8. .
isoform 2 and kinase-defective, as well as full-length isoform 1 are excluded from the nucleus.
Multi-pass membrane protein . Cytoplasm, cytoskeleton. Nucleus. Catalytically active full-length phosphorylated isoform 1 localizes to microtubules in the cytoplasm predominantly on microtubule cables positioned around the nucleus. A C-terminally truncate
[Isoform 2]: Cell projection, dendrite. In dendrites, colocalizes with PCDH8. .
isoform 2 and kinase-defective, as well as full-length isoform 1 are excluded from the nucleus.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
9344
Observed Band
135kD
Background
This gene encodes a serine/threonine protein kinase that is involved in many different processes, including, cell signaling, microtubule organization and stability, and apoptosis. Alternatively spliced transcript variants encoding different isoforms have