Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ELISA 1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Subcellular Location
Endosome membrane
Multi-pass membrane protein . Golgi apparatus membrane . Endosome, multivesicular body membrane .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
54602
Observed Band
36kD
Background
function:May be involved in endocytosis. Regulates ENaC surface expression (By similarity). May be involved in NF-kappa-B and MAPK signaling pathways.,induction:By T-cell activation.,PTM:Ubiquitinated by NEDD4 or NEDD4L
which does not affect turnover.,subunit:Interacts with NEDD4L (By similarity). Interacts with NEDD4.,tissue specificity:Expressed in brain, lung, heart, skeletal muscle, kidney, liver and placenta.,