Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IF
IHC
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 1230-1310
Subcellular Location
Cytoplasm . Cytoplasm, cytoskeleton, spindle . Nucleus . The nuclear-cytoplasmic distribution could be regulated by the availability of calmodulin (By similarity). Localizes to spindle poles during mitosis (PubMed:19690332). Associates with microtubule mi
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
259266
Observed Band
382kD
Background
This gene is the human ortholog of the Drosophila melanogaster 'abnormal spindle' gene (asp), which is essential for normal mitotic spindle function in embryonic neuroblasts. Studies in mouse also suggest a role of this gene in mitotic spindle regulation,