Storage Conditions
-20°C/1 year
Applications
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 2190-2270
Subcellular Location
Cytoplasm, perinuclear region. Nucleus matrix. Chromosome, centromere, kinetochore. Cytoplasm, cytoskeleton, spindle. Relocalizes to the kinetochore/centromere (coronal surface of the outer plate) and the spindle during mitosis. Observed in nucleus during
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1063
Observed Band
353kD
Background
This gene encodes a protein that associates with the centromere-kinetochore complex. The protein is a component of the nuclear matrix during the G2 phase of interphase. In late G2 the protein associates with the kinetochore and maintains this association