Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IF
IHC
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 1280-1360
Subcellular Location
Chromosome . Localizes at replication forks: following DNA damage, localizes to damaged replication forks undergoing resection. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
259282
Observed Band
335kD
Background
Component of the fork protection machinery required to protect stalled/damaged replication forks from uncontrolled DNA2-dependent resection. Acts by stabilizing RAD51 at stalled replication forks and protecting RAD51 nucleofilaments from the antirecombino