Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IF
IHC
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human protein . at AA range: 2890-2970
Subcellular Location
Apical cell membrane
Single-pass type I membrane protein . Endosome lumen . Membrane, coated pit . Cell projection, dendrite . Cell projection, axon . Localizes to brush border membranes in the kidney. In the endolymphatic sac of the inner ear, located in the lumen of endosom
Single-pass type I membrane protein . Endosome lumen . Membrane, coated pit . Cell projection, dendrite . Cell projection, axon . Localizes to brush border membranes in the kidney. In the endolymphatic sac of the inner ear, located in the lumen of endosom
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
4036
Observed Band
512kD
Background
The protein encoded by this gene, low density lipoprotein-related protein 2 (LRP2) or megalin, is a multi-ligand endocytic receptor that is expressed in many different tissues but primarily in absorptive epithilial tissues such as the kidney. This glycopr
extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of th
extracellular ligands include parathyroid horomones and the morphogen sonic hedgehog while cytosolic ligands include MAP kinase scaffold proteins and JNK interacting proteins. Recycling of th