Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ELISA 1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein AA range: 181-230
Subcellular Location
Cell membrane
Single-pass type I membrane protein . Autolysosome membrane . The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation (PubMed:18305173). Componen
Single-pass type I membrane protein . Endoplasmic reticulum membrane
Single-pass type I membrane protein . Late endosome membrane
Single-pass type I membrane protein . Lysosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
3123
Observed Band
29kD
Background
and exon 5 encodes the cytoplasmic tail. Within the DR molecule the beta chain contains all the polymorphisms specifying the peptide binding specificities. Hundreds of DRB1 alleles have been described and typing for these polymorphisms is routinely done f
exon 4 encodes the transmembrane domain
exons 2 and 3 encode the two extracellular domains
major histocompatibility complex, class II, DR beta 1(HLA-DRB1) Homo sapiens HLA-DRB1 belongs to the HLA class II beta chain paralogs. The class II molecule is a heterodimer consisting of an alpha (DRA) and a beta chain (DRB), both anchored in the memb