Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000 ELISA 1:5000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from part region of human protein
Subcellular Location
Cytoplasmic vesicle membrane
Multi-pass membrane protein .
Multi-pass membrane protein . Early endosome membrane
Multi-pass membrane protein . Lysosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
220972
Observed Band
32kD
Background
Bartee et al., 2004 [PubMed 14722266]).[supplied by OMIM, Apr 2010],
MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. M