Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human OGT Polyclonal AA range: 435-475
Subcellular Location
Nucleus . Cytoplasm . Predominantly localizes to the nucleus. .
[Isoform 2]: Mitochondrion . Membrane . Associates with the mitochondrial inner membrane. .
[Isoform 3]: Cytoplasm . Nucleus . Cell membrane . Mitochondrion membrane . Cell projection . Mostly in the nucleus. Retained in the nucleus via interaction with HCFC1 (PubMed:21285374). After insulin induction, translocated from the nucleus to the cell m
[Isoform 4]: Cytoplasm. Nucleus.
[Isoform 2]: Mitochondrion . Membrane . Associates with the mitochondrial inner membrane. .
[Isoform 3]: Cytoplasm . Nucleus . Cell membrane . Mitochondrion membrane . Cell projection . Mostly in the nucleus. Retained in the nucleus via interaction with HCFC1 (PubMed:21285374). After insulin induction, translocated from the nucleus to the cell m
[Isoform 4]: Cytoplasm. Nucleus.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
8473
Observed Band
115kD
Other Name
UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit (EC 2.4.1.255) (O-GlcNAc transferase subunit p110) (O-linked N-acetylglucosamine transferase 110 kDa subunit) (OGT)
Background
This gene encodes a glycosyltransferase that catalyzes the addition of a single N-acetylglucosamine in O-glycosidic linkage to serine or threonine residues. Since both phosphorylation and glycosylation compete for similar serine or threonine residues, the