Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human FAP-1 Polyclonal
Subcellular Location
Single-pass type II membrane protein . Cell projection, invadopodium membrane
Single-pass type II membrane protein . Cell projection, lamellipodium membrane
Single-pass type II membrane protein . Cell projection, ruffle membrane
Single-pass type II membrane protein . Localized on cell surface with lamellipodia and invadopodia membranes and on shed vesicles. Colocalized with DPP4 at invadopodia and lamellipodia membranes of migratory activated endothelial cells in collagenous matr
Single-pass type II membrane protein . Membrane
[Prolyl endopeptidase FAP]: Cell surface . Cell membrane
Single-pass type II membrane protein . Cell projection, lamellipodium membrane
Single-pass type II membrane protein . Cell projection, ruffle membrane
Single-pass type II membrane protein . Localized on cell surface with lamellipodia and invadopodia membranes and on shed vesicles. Colocalized with DPP4 at invadopodia and lamellipodia membranes of migratory activated endothelial cells in collagenous matr
Single-pass type II membrane protein . Membrane
[Prolyl endopeptidase FAP]: Cell surface . Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
2191
Observed Band
150kD
Other Name
Seprase (EC 3.4.21.-) (170 kDa melanoma membrane-bound gelatinase) (Fibroblast activation protein alpha) (Integral membrane serine protease)
Background
The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant