Información del producto
Tau (Phospho-Ser396) Rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
WB
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized phospho derived from human Tau (Phospho-Ser396)
Subcellular Location
Cytoplasm, cytosol . Cell membrane
Cytoplasmic side . Cytoplasm, cytoskeleton . Cell projection, axon . Cell projection, dendrite . Secreted . Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components (PubMed:10747907). Can be secreted
Peripheral membrane protein
it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .
the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10
Cytoplasmic side . Cytoplasm, cytoskeleton . Cell projection, axon . Cell projection, dendrite . Secreted . Mostly found in the axons of neurons, in the cytosol and in association with plasma membrane components (PubMed:10747907). Can be secreted
Peripheral membrane protein
it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059). .
the secretion is dependent on protein unfolding and facilitated by the cargo receptor TMED10
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
4137
Observed Band
50-85kD
Other Name
Microtubule-associated protein tau (Neurofibrillary tangle protein) (Paired helical filament-tau) (PHF-tau)
Background
This gene encodes the microtubule-associated protein tau (MAPT) whose transcript undergoes complex, regulated alternative splicing, giving rise to several mRNA species. MAPT transcripts are differentially expressed in the nervous system, depending on stag