Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p: 100-300.WB 1:500-2000, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from human Thioredoxin. at AA range: 52-101
Subcellular Location
Nucleus . Cytoplasm . Secreted . Translocates from the cytoplasm into the nucleus after phorbol 12-myristate 13-acetate induction (PMA) (PubMed:9108029). Predominantly in the cytoplasm in non irradiated cells (PubMed:11118054). Radiation induces transloca
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
7295
Observed Band
12kD
Other Name
ADF
ATL-derived factor
SASP)
Surface-associated sulphydryl protein
Thioredoxin (Trx
Background
The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. Th