Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthetic peptide from human protein at AA range: 207-256
Subcellular Location
Secreted. Cytoplasmic granule. Granules of large granular lymphocytes.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
3004
Other Name
Granzyme M (EC 3.4.21.-
Hu-Met-1
Met-1 serine protease
Met-ase
Natural killer cell granular protease)
Background
Human natural killer (NK) cells and activated lymphocytes express and store a distinct subset of neutral serine proteases together with proteoglycans and other immune effector molecules in large cytoplasmic granules. These serine proteases are collectivel