Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-200, ELISA 1:10000-20000 IF 1:100-300 Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthetic peptide from human protein at AA range: 181-230
Subcellular Location
Cell membrane
Single-pass type I membrane protein .
Single-pass type I membrane protein .
Single-pass type I membrane protein . Associates with CMTM6 at recycling endosomes, where it is protected from being targeted for lysosomal degradation. .
Single-pass type I membrane protein . Early endosome membrane
Single-pass type I membrane protein . Recycling endosome membrane
[Isoform 1]: Cell membrane
[Isoform 2]: Endomembrane system
Single-pass type I membrane protein .
Single-pass type I membrane protein .
Single-pass type I membrane protein . Associates with CMTM6 at recycling endosomes, where it is protected from being targeted for lysosomal degradation. .
Single-pass type I membrane protein . Early endosome membrane
Single-pass type I membrane protein . Recycling endosome membrane
[Isoform 1]: Cell membrane
[Isoform 2]: Endomembrane system
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
29126
Other Name
Programmed cell death 1 ligand 1 (PD-L1) (PDCD1 ligand 1) (Programmed death ligand 1) (B7 homolog 1) (B7-H1) (CD antigen CD274)
Background
This gene encodes an immune inhibitory receptor ligand that is expressed by hematopoietic and non-hematopoietic cells, such as T cells and B cells and various types of tumor cells. The encoded protein is a type I transmembrane protein that has immunoglobu