Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human HLA-DQA1. AA range:21-70
Subcellular Location
Cell membrane
Single-pass type I membrane protein. Endoplasmic reticulum membrane
Single-pass type I membrane protein. Endosome membrane
Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane
Single-pass type I membrane protein. Lysosome membrane
Single-pass type I membrane protein. The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation.
Single-pass type I membrane protein. Endoplasmic reticulum membrane
Single-pass type I membrane protein. Endosome membrane
Single-pass type I membrane protein. Golgi apparatus, trans-Golgi network membrane
Single-pass type I membrane protein. Lysosome membrane
Single-pass type I membrane protein. The MHC class II complex transits through a number of intracellular compartments in the endocytic pathway until it reaches the cell membrane for antigen presentation.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Human Gen
100509457
Other Name
DC-alpha
HLA-DCA
HLA class II histocompatibility antigen, DQ alpha 1 chain (DC-1 alpha chain
MHC class II DQA1)
HLA-DCA
HLA class II histocompatibility antigen, DQ alpha 1 chain (DC-1 alpha chain
MHC class II DQA1)
Background
HLA-DQA1 belongs to the HLA class II alpha chain paralogues. The class II molecule is a heterodimer consisting of an alpha (DQA) and a beta chain (DQB), both anchored in the membrane. It plays a central role in the immune system by presenting peptides der
exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifyin
exon 1 encodes the leader peptide, exons 2 and 3 encode the two extracellular domains, and exon 4 encodes the transmembrane domain and the cytoplasmic tail. Within the DQ molecule both the alpha chain and the beta chain contain the polymorphisms specifyin