Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-200, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthetic peptide from human protein at AA range: 101-150
Subcellular Location
Cytoplasm, cytosol . Nucleus . Secreted . Stimulation with IL1B leads to colocalization with SMAD3 mostly in perinuclear regions (PubMed:20935647, PubMed:33674380). Only the CASP1-cleaved mature form translocates into the nucleus upon LPS stimulation (Pub
it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059, PubMed:33674380). .
it results in protein translocation from the cytoplasm into the ERGIC (endoplasmic reticulum-Golgi intermediate compartment) followed by vesicle entry and secretion (PubMed:32272059, PubMed:33674380). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
27178
Other Name
IL-1 zeta
IL-1F7
IL-1H
IL-1H4
IL-1RP1
IL-1X
IL-37)
Interleukin-1 family member 7
Interleukin-1 homolog 4
Interleukin-1 zeta
Interleukin-1-related protein
Interleukin-23
Interleukin-37 (FIL1 zeta
IL-1F7
IL-1H
IL-1H4
IL-1RP1
IL-1X
IL-37)
Interleukin-1 family member 7
Interleukin-1 homolog 4
Interleukin-1 zeta
Interleukin-1-related protein
Interleukin-23
Interleukin-37 (FIL1 zeta
Background
The protein encoded by this gene is a member of the interleukin 1 cytokine family. This cytokine can bind to, and may be a ligand for interleukin 18 receptor (IL18R1/IL-1Rrp). This cytokine also binds to interleukin 18 binding protein (IL18BP), an inhibit