Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthetic peptide from human protein at AA range: 261-310
Subcellular Location
Cell surface . Lysosome membrane
Single-pass type I membrane protein . Cytoplasmic vesicle membrane
Single-pass type I membrane protein . During dendritic cell maturation, detected on cytoplasmic vesicles (the MHC II compartment) that contain MHC II proteins, LAMP1, LAMP2 and LAMP3 (PubMed:9768752). Detected on lysosomes in mature dendritic cells (PubMe
Single-pass type I membrane protein . Early endosome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
27074
Observed Band
44kD
Other Name
CD antigen CD208)
DC-lysosome-associated membrane glycoprotein
DC LAMP
Lysosomal-associated membrane protein 3
Lysosome-associated membrane glycoprotein 3 (LAMP-3
Protein TSC403
Background
Dendritic cells (DCs) are the most potent antigen-presenting cells. Immature DCs efficiently capture antigens and differentiate into interdigitating dendritic cells (IDCs) in lymphoid tissues that induce primary T-cell responses (summary by de Saint-Vis e