Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000,IHC-p 1:50-200, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthetic peptide from human protein at AA range: 31-80
Subcellular Location
Single-pass type I membrane protein .
Single-pass type I membrane protein .
[Isoform 1]: Cell membrane
[Isoform 2]: Endomembrane system
[Isoform 3]: Secreted .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
80380
Observed Band
30kD
Other Name
B7-DC
Butyrophilin B7-DC
CD antigen CD273)
PD-L2
PDCD1 ligand 2
Programmed cell death 1 ligand 2 (PD-1 ligand 2
Programmed death ligand 2
Background
function:Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.,induction