Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthetic peptide from human protein at AA range: 3850-3900
Subcellular Location
Nucleus .
[MLL cleavage product C180]: Nucleus. Localizes to a diffuse nuclear pattern when not associated with MLL cleavage product N320.
[MLL cleavage product N320]: Nucleus.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
4297
Other Name
ALL-1
CXXC-type zinc finger protein 7
Histone-lysine N-methyltransferase MLL (EC 2.1.1.43
KMT2A
Lysine N-methyltransferase 2A
MLL cleavage product C180 (C-terminal cleavage product of 180 kDa
Trithorax-like protein
Zinc finger protein HRX) [Cleaved into: MLL cleavage product N320 (N-terminal cleavage product of 320 kDa
p180)]
p320)
Background
This gene encodes a transcriptional coactivator that plays an essential role in regulating gene expression during early development and hematopoiesis. The encoded protein contains multiple conserved functional domains. One of these domains, the SET domain