Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthetic peptide from human protein at AA range: 640-700
Subcellular Location
Cell membrane
Single-pass type I membrane protein.
Single-pass type I membrane protein. Cytoplasm . Nucleus . Ligand-mediated autophosphorylation leads to rapid internalization. .
Single-pass type I membrane protein. Ligand-mediated autophosphorylation leads to rapid internalization.
[Isoform 1]: Cell membrane
[Isoform 2]: Cell membrane
[Isoform 3]: Secreted. Cytoplasm.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
2324
Observed Band
170kD
Other Name
EC 2.7.10.1
FLT-4
Fms-like tyrosine kinase 4
Tyrosine-protein kinase receptor FLT4)
Vascular endothelial growth factor receptor 3 (VEGFR-3
Background
This gene encodes a tyrosine kinase receptor for vascular endothelial growth factors C and D. The protein is thought to be involved in lymphangiogenesis and maintenance of the lymphatic endothelium. Mutations in this gene cause hereditary lymphedema type