Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IHC-f
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000,IHC-p 1:500-200, ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthetic peptide from human protein at AA range: 220-280
Subcellular Location
Cell membrane
Multi-pass membrane protein . Localizes in synaptosomes at dendritic synapses of neurons. Colocalizes with DLG4 (By similarity). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
41
Observed Band
55kD
Other Name
Acid-sensing ion channel 1 (ASIC1
Amiloride-sensitive cation channel 2, neuronal
BNaC2)
Brain sodium channel 2
Background
This gene encodes a member of the acid-sensing ion channel (ASIC) family of proteins, which are part of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. Members of the ASIC family are sensitive to amiloride and function in neurotransmission