Información del producto
Flk-1/VEGFR2 rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. IHC-p: 1:100-300 ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthetic peptide from human protein at AA range: 1268-1341
Subcellular Location
Cell junction . Endoplasmic reticulum . Cell membrane . Localized with RAP1A at cell-cell junctions (By similarity). Colocalizes with ERN1 and XBP1 in the endoplasmic reticulum in endothelial cells in a vascular endothelial growth factor (VEGF)-dependent
Single-pass type I membrane protein. Cytoplasm. Nucleus. Cytoplasmic vesicle. Early endosome. Detected on caveolae-enriched lipid rafts at the cell surface. Is recycled from the plasma membrane to endosomes and back again. Phosphorylation triggered by VEG
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted .
[Isoform 3]: Secreted.
Single-pass type I membrane protein. Cytoplasm. Nucleus. Cytoplasmic vesicle. Early endosome. Detected on caveolae-enriched lipid rafts at the cell surface. Is recycled from the plasma membrane to endosomes and back again. Phosphorylation triggered by VEG
[Isoform 1]: Cell membrane
[Isoform 2]: Secreted .
[Isoform 3]: Secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Human Gen
3791
Other Name
CD antigen CD309)
EC 2.7.10.1
FLK-1
Fetal liver kinase 1
KDR
Kinase insert domain receptor
Protein-tyrosine kinase receptor flk-1
Vascular endothelial growth factor receptor 2 (VEGFR-2
EC 2.7.10.1
FLK-1
Fetal liver kinase 1
KDR
Kinase insert domain receptor
Protein-tyrosine kinase receptor flk-1
Vascular endothelial growth factor receptor 2 (VEGFR-2
Background
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions a