Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
WB 1:500-2000,IHC-p 1:50-200 ELISA 1:10000-20000
Type Clonality
Polyclonal
Immunogen
Synthetic peptide from human protein at AA range: 301-350
Subcellular Location
Nucleus . Chromosome . Cytoplasm . Predominantly nuclear in interphase cells (PubMed:12194828). Binds to mitotic chromosomes (PubMed:12194828, PubMed:17435751, PubMed:20668449). .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
1104
Observed Band
45kD
Other Name
RCC1 CHC1
Background
disease:Patients with Raynaud disease produce antibodies that bind to RCC1.,function:Promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds to the chromatin. RCC1/Ran complex (to