Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from ASAH3L . at AA range: 50-130
Subcellular Location
Golgi apparatus membrane
Multi-pass membrane protein .
Multi-pass membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Monkey
Mouse
Monkey
Mouse
Human Gen
340485
Observed Band
33kD
Other Name
ACER2
ASAH3L
Acylsphingosine deacylase 3-like
AlkCDase 2
Alkaline CDase 2
Alkaline ceramidase 2
N-acylsphingosine amidohydrolase 3-like
PP11646
haCER2
ASAH3L
Acylsphingosine deacylase 3-like
AlkCDase 2
Alkaline CDase 2
Alkaline ceramidase 2
N-acylsphingosine amidohydrolase 3-like
PP11646
haCER2
Background
The sphingolipid metabolite sphingosine-1-phosphate promotes cell proliferation and survival, whereas its precursor, sphingosine, has the opposite effect. The ceramidase ACER2 hydrolyzes very long chain ceramides to generate sphingosine (Xu et al., 2006 [