Información del producto
Neuregulin-3 rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. IHC-p: 1:100-1:300. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human NRG3. AA range:311-360
Subcellular Location
Single-pass type I membrane protein . Does not seem to be active. .
Single-pass type I membrane protein. Isoform 3 is also proteolytically released as a soluble form.
[Isoform 3]: Cell membrane
[Neuregulin-3]: Secreted .
[Pro-neuregulin-3, membrane-bound isoform]: Cell membrane
Single-pass type I membrane protein. Isoform 3 is also proteolytically released as a soluble form.
[Isoform 3]: Cell membrane
[Neuregulin-3]: Secreted .
[Pro-neuregulin-3, membrane-bound isoform]: Cell membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
10718
Observed Band
80kD
Other Name
NRG3
Pro-NRG3
Pro-neuregulin-3, membrane-bound isoform
Pro-NRG3
Pro-neuregulin-3, membrane-bound isoform
Background
This gene is a member of the neuregulin gene family. This gene family encodes ligands for the transmembrane tyrosine kinase receptors ERBB3 and ERBB4 - members of the epidermal growth factor receptor family. Ligand binding activates intracellular signalin