Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from ASAH3 . at AA range: 100-180
Subcellular Location
Endoplasmic reticulum membrane
Multi-pass membrane protein .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
125981
Observed Band
34kD
Other Name
ACER1
ASAH3
Acylsphingosine deacylase 3
AlkCDase 1
Alkaline CDase 1
Alkaline ceramidase 1
N-acylsphingosine amidohydrolase 3
Background
Ceramides are synthesized during epidermal differentiation and accumulate within the interstices of the stratum corneum, where they represent critical components of the epidermal permeability barrier. Excess cellular ceramide can trigger antimitogenic sig
Sun et al., 2008 [PubMed 17713573]).[supplied by OMIM, Jul 2010],