Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from Topo IIIα . at AA range: 350-430
Subcellular Location
Mitochondrion matrix .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Human Gen
7156
Observed Band
115kD
Other Name
DNA topoisomerase 3-alpha
DNA topoisomerase III alpha
TOP3
TOP3A
Background
This gene encodes a DNA topoisomerase, an enzyme that controls and alters the topologic states of DNA during transcription. This enzyme catalyzes the transient breaking and rejoining of a single strand of DNA which allows the strands to pass through one a