Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NR1I3. AA range:71-120
Subcellular Location
Nucleus. Cytoplasm. Cytoplasm, cytoskeleton. Recruited to the cytoplasm by DNAJC7. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
9970
Observed Band
35kD
Other Name
CAR
CAR
Constitutive activator of retinoid response
Constitutive active response
Constitutive androstane receptor
NR1I3
Nuclear receptor subfamily 1 group I member 3
Orphan nuclear receptor MB67
Background
This gene encodes a member of the nuclear receptor superfamily, and is a key regulator of xenobiotic and endobiotic metabolism. The protein binds to DNA as a monomer or a heterodimer with the retinoid X receptor and regulates the transcription of target g