Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
IHC
WB
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human RAPGEF5. AA range:431-480
Subcellular Location
Nucleus.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
9771
Observed Band
60kD
Other Name
GFR
Guanine nucleotide exchange factor for Rap1
KIAA0277
M-Ras-regulated Rap GEF
MR-GEF
MRGEF
RAPGEF5
Rap guanine nucleotide exchange factor 5
Related to Epac
Repac
Guanine nucleotide exchange factor for Rap1
KIAA0277
M-Ras-regulated Rap GEF
MR-GEF
MRGEF
RAPGEF5
Rap guanine nucleotide exchange factor 5
Related to Epac
Repac
Background
MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting
Members of the RAS (see HRAS
Members of the RAS (see HRAS