Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human AKAP12. AA range:301-350
Subcellular Location
Cytoplasm, cell cortex . Cytoplasm, cytoskeleton . Membrane
Lipid-anchor . May be part of the cortical cytoskeleton.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
9590
Other Name
A-kinase anchor protein 12
A-kinase anchor protein 250 kDa
AKAP-12
AKAP12
AKAP250
AKAP 250
Gravin
Myasthenia gravis autoantigen
Background
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene