Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IF: 1:50-200 Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human EIF2AK3. AA range:947-996
Subcellular Location
Endoplasmic reticulum membrane
Single-pass type I membrane protein.
Single-pass type I membrane protein.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
9451
Observed Band
125kD
Other Name
EIF2AK3
Eukaryotic translation initiation factor 2-alpha kinase 3
HsPEK
PEK
PERK
PRKR-like endoplasmic reticulum kinase
Pancreatic eIF2-alpha kinase
Eukaryotic translation initiation factor 2-alpha kinase 3
HsPEK
PEK
PERK
PRKR-like endoplasmic reticulum kinase
Pancreatic eIF2-alpha kinase
Background
The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protei