Storage Conditions
-20°C/1 year
Applications
ELISA
IF
Concentration
1 mg/ml
Recomended Dilution
Immunofluorescence: 1/200 - 1/1000. ELISA: 1/10000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human HAND1. AA range:141-190
Subcellular Location
Nucleus, nucleoplasm . Nucleus, nucleolus . Interaction with MDFIC sequesters it into the nucleolus, preventing the transcription factor activity. Phosphorylation by PLK4 disrupts the interaction with MDFIC and releases it from the nucleolus, leading to t
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
9421
Other Name
BHLHA27
Class A basic helix-loop-helix protein 27
EHAND
Extraembryonic tissues
HAND1
Heart- and neural crest derivatives-expressed protein 1
bHLHa27
eH
heart, autonomic nervous system and neural crest derivatives-expressed protein 1
Background
The protein encoded by this gene belongs to the basic helix-loop-helix family of transcription factors. This gene product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular cha