Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human BL-CAM around the phosphorylation site of Tyr807. AA range:776-825
Subcellular Location
Cell membrane
Single-pass type I membrane protein.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
933
Observed Band
95kD
Other Name
B-cell receptor CD22
B-lymphocyte cell adhesion molecule
BL-CAM
CD22
CD antigen CD22
SIGLEC2
Sialic acid-binding Ig-like lectin 2
Siglec-2
T-cell surface antigen Leu-14
Background
alternative products:Additional isoforms seem to exist,domain:Contains 4 copies of a cytoplasmic motif that is referred to as the immunoreceptor tyrosine-based inhibitor motif (ITIM). This motif is involved in modulation of cellular responses. The phospho
one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response