Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human DYR1B. AA range:331-380
Subcellular Location
Nucleus . Nucleus, nucleolus . Chromosome . Localizes to sites of double-strand breaks (DSBs) following DNA damage. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
9149
Observed Band
70kD
Other Name
DYRK1B
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
MIRK
Minibrain-related kinase
Mirk protein kinase
Dual specificity tyrosine-phosphorylation-regulated kinase 1B
MIRK
Minibrain-related kinase
Mirk protein kinase
Background
This gene encodes a member of a family of nuclear-localized protein kinases. The encoded protein participates in the regulation of the cell cycle. Expression of this gene may be altered in tumor cells, and mutations in this gene were found to cause abdomi