Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
Synthesized peptide derived from Duo . at AA range: 810-890
Subcellular Location
Cytoplasm . Cytoplasm, cytoskeleton . Associated with the cytoskeleton.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
8997
Other Name
DUET
DUO
HAPIP
Huntingtin-associated protein-interacting protein
KALRN
Kalirin
Protein Duo
Serine/threonine-protein kinase with Dbl- and pleckstrin homology domain
TRAD
Background
Huntington's disease (HD), a neurodegenerative disorder characterized by loss of striatal neurons, is caused by an expansion of a polyglutamine tract in the HD protein huntingtin. This gene encodes a protein that interacts with the huntingtin-associated p