Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human BCL10. AA range:111-160
Subcellular Location
Cytoplasm, perinuclear region . Membrane raft . Appears to have a perinuclear, compact and filamentous pattern of expression. Also found in the nucleus of several types of tumor cells. Colocalized with DPP4 in membrane rafts. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
8915
Observed Band
36kD
Other Name
B-cell CLL/lymphoma 10
B-cell lymphoma/leukemia 10
BCL10
Bcl-10
CARD-containing molecule enhancing NF-kappa-B
CARD-like apoptotic protein
CED-3/ICH-1 prodomain homologous E10-like regulator
CIPER
CIPER
CLAP
Cellular homolog
hCLAP
B-cell lymphoma/leukemia 10
BCL10
Bcl-10
CARD-containing molecule enhancing NF-kappa-B
CARD-like apoptotic protein
CED-3/ICH-1 prodomain homologous E10-like regulator
CIPER
CIPER
CLAP
Cellular homolog
hCLAP
Background
This gene was identified by its translocation in a case of mucosa-associated lymphoid tissue (MALT) lymphoma. The protein encoded by this gene contains a caspase recruitment domain (CARD), and has been shown to induce apoptosis and to activate NF-kappaB.