Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human MTG16. AA range:261-310
Subcellular Location
[Isoform 1]: Nucleus, nucleolus. The RUNX1-CBFA2T3 fusion protein localizes to the nucleoplasm.
[Isoform 2]: Nucleus, nucleoplasm . Golgi apparatus membrane .
[Isoform 2]: Nucleus, nucleoplasm . Golgi apparatus membrane .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
863
Other Name
CBFA2T3
MTG8-related protein 2
MTG16
MTGR2
Myeloid translocation gene on chromosome 16 protein
Protein CBFA2T3
ZMYND4
Zinc finger MYND domain-containing protein 4
hMTG16
MTG8-related protein 2
MTG16
MTGR2
Myeloid translocation gene on chromosome 16 protein
Protein CBFA2T3
ZMYND4
Zinc finger MYND domain-containing protein 4
hMTG16
Background
21)(q24
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16
q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This
This gene encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression. The t(16
q22) translocation is one of the less common karyotypic abnormalities in acute myeloid leukemia. The translocation produces a chimeric gene made up of the 5'-region of the runt-related transcription factor 1 gene fused to the 3'-region of this gene. This