Storage Conditions
-20°C/1 year
Applications
ELISA
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human AML1 around the phosphorylation site of Ser276. AA range:242-291
Subcellular Location
Nucleus.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
861
Observed Band
49kD
Other Name
AML1
Acute myeloid leukemia 1 protein
CBF-alpha-2
CBFA2
Core-binding factor subunit alpha-2
Oncogene AML-1
PEA2-alpha B
PEBP2-alpha
Polyomavirus enhancer-binding protein 2 alpha B subunit
RUNX1
Runt-related transcription factor 1
Background
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of norm