Información del producto
IKKγ (phospho Ser376) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human IKK-gamma around the phosphorylation site of Ser376. AA range:342-391
Subcellular Location
Cytoplasm . Nucleus . Sumoylated NEMO accumulates in the nucleus in response to genotoxic stress. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Mouse
Rat
Human Gen
8517
Other Name
FIP-3
FIP3
I-kappa-B kinase subunit gamma
IKBKG
IKK-gamma
IKKAP1
IKKG
IkB kinase-associated protein 1
IkB kinase subunit gamma
Inhibitor of nuclear factor kappa-B kinase subunit gamma
NEMO
NEMO
NF
NF-kappa-B essential modulator
FIP3
I-kappa-B kinase subunit gamma
IKBKG
IKK-gamma
IKKAP1
IKKG
IkB kinase-associated protein 1
IkB kinase subunit gamma
Inhibitor of nuclear factor kappa-B kinase subunit gamma
NEMO
NEMO
NF
NF-kappa-B essential modulator
Background
This gene encodes the regulatory subunit of the inhibitor of kappaB kinase (IKK) complex, which activates NF-kappaB resulting in activation of genes involved in inflammation, immunity, cell survival, and other pathways. Mutations in this gene result in in