Storage Conditions
-20°C/1 year
Applications
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
IHC-p 1:50-300
WB 1:500-2000
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human NFATC2IP. AA range:151-200
Subcellular Location
Nucleus . Cytoplasm . TRAF1 is associated with a fraction of NFATC2IP in the cytoplasm and prevents its translocation to the nucleus. .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Fish
Human
Mouse
Rat
Human Gen
84901
Observed Band
48kD
Other Name
45 kDa NF-AT-interacting protein
45 kDa NFAT-interacting protein
NFATC2-interacting protein
NFATC2IP
NIP45
Nuclear factor of activated T-cells
cytoplasmic 2-interacting protein
Background
function:Plays a role in the inducible expression of cytokine genes in T-cells, especially by increasing NFAT-driven IL-4 production.,PTM:Methylation at the N-terminus by PRMT1 modulates interaction with the NFAT complex and results in augmented cytokine