Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. Immunofluorescence: 1/200 - 1/1000. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Collagen XXV alpha1. AA range:101-150
Subcellular Location
Membrane
Single-pass type II membrane protein . After proteolytic cleavage, CLAC is secreted.
Single-pass type II membrane protein . After proteolytic cleavage, CLAC is secreted.
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
84570
Observed Band
64kD
Other Name
AMY
Alzheimer disease amyloid-associated protein
CLAC-P
COL25A1
Collagen alpha-1(XXV) chain
Alzheimer disease amyloid-associated protein
CLAC-P
COL25A1
Collagen alpha-1(XXV) chain
Background
This gene encodes a brain-specific membrane associated collagen. A product of proteolytic processing of the encoded protein, CLAC (collagenous Alzheimer amyloid plaque component), binds to amyloid beta-peptides found in Alzheimer amyloid plaques but CLAC