Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/20000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human GNPAT. AA range:231-280
Subcellular Location
Matrix side . Exclusively localized to the lumenal side of the peroxisomal membrane. .
Peripheral membrane protein
Peroxisome membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Rat
Human Gen
8443
Observed Band
77kD
Other Name
Acyl-CoA:dihydroxyacetonephosphateacyltransferase
DAP-AT
DAPAT
DHAP-AT
DHAPAT
Dihydroxyacetone phosphate acyltransferase
GNPAT
Glycerone-phosphate O-acyltransferase
Background
This gene encodes an enzyme located in the peroxisomal membrane which is essential to the synthesis of ether phospholipids. Mutations in this gene are associated with rhizomelic chondrodysplasia punctata. Two transcript variants encoding different isoform