Información del producto
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
IF
IHC
Concentration
1 mg/ml
Recomended Dilution
Immunohistochemistry: 1/100 - 1/300. ELISA: 1/40000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human C9orf89. AA range:21-70
Subcellular Location
Single-pass membrane protein .
Single-pass membrane protein . Mitochondrion membrane
[Isoform 1]: Nucleus . Coexpression with BCL10 induced translocation from nucleus to cytosol.
[Isoform 2]: Endoplasmic reticulum membrane
Single-pass membrane protein . Mitochondrion membrane
[Isoform 1]: Nucleus . Coexpression with BCL10 induced translocation from nucleus to cytosol.
[Isoform 2]: Endoplasmic reticulum membrane
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Mouse
Mouse
Human Gen
84270
Other Name
Bcl10-interacting CARD protein
BinCARD
C9orf89
BinCARD
C9orf89
Background
function:Plays a role in inhibiting the effects of BCL10-induced activation of NF-kappa-B. May inhibit the phosphorylation of BCL10 in a CARD-dependent manner.,PTM:Isoform 2 is phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1