Información del producto
Caspase-8 (phospho Ser347) rabbit pAb
Información adicional
Storage Conditions
-20°C/1 year
Applications
ELISA
IF
IHC
WB
IF
IHC
WB
Concentration
1 mg/ml
Recomended Dilution
Western Blot: 1/500 - 1/2000. Immunohistochemistry: 1/100 - 1/300. ELISA: 1/5000. Not yet tested in other applications.
Type Clonality
Polyclonal
Immunogen
The antiserum was produced against synthesized peptide derived from human Caspase 8 around the phosphorylation site of Ser347. AA range:313-362
Subcellular Location
Cytoplasm . Nucleus .
Iso type
IgG
Tissue Source
Rabbit
Reactivity
Human
Rat
Rat
Human Gen
841
Observed Band
55kD
Other Name
Apoptotic cysteine protease
Apoptotic protease Mch-5
CAP4
CASP-8
CASP8
Caspase-8
FADD-homologous ICE/ced-3-like protease
FADD-like ICE
FLICE
ICE-like apoptotic protease 5
MACH
MCH5
MORT1-associated ced-3 homolog
Apoptotic protease Mch-5
CAP4
CASP-8
CASP8
Caspase-8
FADD-homologous ICE/ced-3-like protease
FADD-like ICE
FLICE
ICE-like apoptotic protease 5
MACH
MCH5
MORT1-associated ced-3 homolog
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain, a large pro